Lyme borreliosis is endemic in the Aland Islands. Exposure of the inha
bitants to bites of the tick Ixodes ricinus is heavy. The purpose of t
his study was to describe symptoms and signs of patients with late Lym
e borreliosis in this area, and to correlate the findings with the epi
demiological setting. The first 100 consecutive patients with late Lym
e borrellosis found in the region since 1984 are included in this stud
y. Neurological, articular and muscular symptoms and signs dominate. G
eneral screening for Lyme disease is not recommended in the area due t
o uncertainty about how to deal with seropositive healthy persons in t
his heavily exposed population. The recognition and prompt treatment o
f erythema migrans and other manifestations of primary Lyme borrellosi
s is important in order to avoid the late stages of the disease. Treat
ment of all those suffering tick-bites with an antibiotic would be an
option in view of the incidence of infected ticks, but cannot be consi
dered because tick-bites are extremely common among the inhabitants. T
he region would be suitable for general immunization against Borrelia
burgdorferi if the means for doing this becomes available in the futur
e.