A crucial problem in building a multiple regression model is the selec
tion of predictors to include. The main thrust of this article is to p
ropose and develop a procedure that uses probabilistic considerations
for selecting promising subsets. This procedure entails embedding the
regression setup in a hierarchical normal mixture model where latent v
ariables are used to identify subset choices. In this framework the pr
omising subsets of predictors can be identified as those with higher p
osterior probability. The computational burden is then alleviated by u
sing the Gibbs sampler to indirectly sample from this multinomial post
erior distribution on the set of possible subset choices. Those subset
s with higher probability-the promising ones-can then be identified by
their more frequent appearance in the Gibbs sample.