Gadolinium enhancement may be normal in the vertebral endplates adjace
nt to previously operated inter-vertebral discs. To determine the freq
uency of this finding and to differentiate this normal healing process
from early lesions due to focal infection, we studied 135 patients wh
o had undergone surgery for herniated lumbar disc, and compared them w
ith 249 unoperated patients with radicular symptoms and 15 with known
spondylodiscitis. Hypo-intense foci which enhanced with gadolinium wer
e identified in the endplates of 25 (18.5%) of the operated patients,
9 of whom required a second operation for recurrent disc herniation, a
t which time the absence of infection was confirmed. Gadolinium enhanc
ement within the end-plates adjacent to the operated disc occurs durin
g normal healing after surgery. Care should be taken before invoking a
diagnosis of focal infection or secondary spondylodiscitis.