AN ADULT CASE OF FANCONI SYNDROME DUE TO A MIXTURE OF CHINESE CRUDE DRUGS

We examined a 35-year-old male case of acquired Fanconi syndrome induc ed by a mixture of Chinese crude drugs. Renal glycosuria, hypokalemia, hypophosphatemia, metabolic acidosis, a low threshold of tubular bica rbonate excretion, and generalized aminoaciduria were observed after t he patient had taken the drugs for 6 months. When he stopped taking th em, all laboratory data improved. He took the drugs again on his own j udgment, leading to a second bout of Fanconi syndrome. This is the fir st case in which Chinese crude drugs have been known to cause acquired Fanconi syndrome.