THE MECHANISM OF FORMATION OF 6-ARYL-4,6-DIOXOHEXANOIC ACIDS FROM ARYLKETONES AND SUCCINIC ANHYDRIDE

Authors
MURRAY WV LALAN P CONNOLLY PJ
Citation
Wv. Murray et al., THE MECHANISM OF FORMATION OF 6-ARYL-4,6-DIOXOHEXANOIC ACIDS FROM ARYLKETONES AND SUCCINIC ANHYDRIDE, Tetrahedron letters, 34(33), 1993, pp. 5189-5192
Citations number
2
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
34
Issue
33
Year of publication
1993
Pages
5189 - 5192
Database
ISI
SICI code
0040-4039(1993)34:33<5189:TMOFO6>2.0.ZU;2-#
Abstract
Compounds 2a-d could be synthesized directly from the requisite acetop henone enolate and succinic anhydride. Intermediate O-acylated product s 1a-d were observed. Compounds 1a-d could be converted to 2a-d by tre atment with at least two additional equivalents of the acetophenone en olate. Evidence indicates that 1 is an intermediate in the synthesis o f 2 and that the direct reaction requires at least two equivalents of acetophenone enolate.