A NEW CONVENIENT PROCEDURE FOR THE SYNTHESIS OF PYRROLO[2,1-C][1,4]BENZODIAZEPINES

Authors
COURTNEY SM THURSTON DE
Citation
Sm. Courtney et De. Thurston, A NEW CONVENIENT PROCEDURE FOR THE SYNTHESIS OF PYRROLO[2,1-C][1,4]BENZODIAZEPINES, Tetrahedron letters, 34(33), 1993, pp. 5327-5328
Citations number
10
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
34
Issue
33
Year of publication
1993
Pages
5327 - 5328
Database
ISI
SICI code
0040-4039(1993)34:33<5327:ANCPFT>2.0.ZU;2-T
Abstract
An efficient synthesis of the pyrrolo[2,1-c] [1,4]benzodiazepine (PBD) ring system based on a new cyclisation procedure is reported. The par ent unsubstituted PBD (4a) and the benzyl derivative (4b) of the natur al product DC-81 (4c) have been synthesized to illustrate the utility of this procedure.