Acromegaly is regarded as a cause for secondary osteoporosis, whereas
recent papers suggest that growth hormone increases bone mineral densi
ty (BMD). In 16 patients with active acromegaly we found an increased
BMD compared to normal controls in the lumbar spine and the proximal f
emur by means of dual energy X-ray absoptiometry. This increase in BMD
was statistically significant in the femoral neck and in Ward's trian
gle (P =0.05). Moreover no signs of osteoporosis were found radiologic
ally.