Nr. Boeree et al., DEVELOPMENT OF A DEGRADABLE COMPOSITE FOR ORTHOPEDIC USE - MECHANICALEVALUATION OF AN HYDROXYAPATITE POLYHYDROXYBUTYRATE COMPOSITE-MATERIAL, Biomaterials, 14(10), 1993, pp. 793-796
This study evaluates the mechanical properties of a composite material
comprising polyhydroxybutyrate with hydroxyapatite added in proportio
ns varying from 0 to 50%. Among the three methods of production, injec
tion moulding was found to result in the most satisfactory mechanical
properties. The tensile and compressive strength and the modulus of el
asticity of composite produced in this way fell within the range for f
resh human bone from different anatomical sites. With the additional a
dvantages of biocompatability, biodegradability and the potential for
piezoelectric stimulation of new local bone formation, it was conclude
d that the injection-moulded composite material has considerable poten
tial for use in orthopaedic surgery, both as a material to construct c
ertain orthopaedic implants and as an alternative to cortico-cancellou
s bone graft.