ISOLATION AND CLONING BY A POLYMERASE CHAIN-REACTION OF A GENOMIC DNAFRAGMENT OF THE HUMAN SLOW SKELETAL TROPONIN (TNNT1) GENE

Authors
NOVELLI G GENNARELLI M SANGIUOLO F DAGRUMA L LOCICERO S MELCHIONDA S DALLAPICCOLA B
Citation
G. Novelli et al., ISOLATION AND CLONING BY A POLYMERASE CHAIN-REACTION OF A GENOMIC DNAFRAGMENT OF THE HUMAN SLOW SKELETAL TROPONIN (TNNT1) GENE, Cell biochemistry and function, 11(3), 1993, pp. 187-191
Citations number
19
Categorie Soggetti
Biology
Journal title
Cell biochemistry and function → ACNP
ISSN journal
02636484
Volume
11
Issue
3
Year of publication
1993
Pages
187 - 191
Database
ISI
SICI code
0263-6484(1993)11:3<187:IACBAP>2.0.ZU;2-R
Abstract
The genomic 3' structure of the gene coding for the human slow skeleta l troponin T (TNNT1) gene, is reported. An intron of 912 nucleotides c ontaining an Alu-element has been identified and characterized. The co mplexity of the sequenced region suggests an alternative exon use. The present results may be valuable for further studies on the gene struc ture of TNNT1 and the related troponin gene family.