J. Hollande et al., COMPARISON OF THE HEMODYNAMIC-RESPONSE TO LARYNGEAL MASK INSERTION AND OROTRACHEAL INTUBATION, Annales francaises d'anesthesie et de reanimation, 12(4), 1993, pp. 372-375
This prospective study was designed to compare the haemodynamic respon
se to insertion of either a laryngeal mask or an orotracheal tube. Twe
nty patients scheduled for orthopaedic surgery were randomly assigned
to two groups : laryngeal mask group (n = 10) and orotracheal tube gro
up (n = 10). Patients were premedicated with flunitrazepam (1 mg i.m.)
and anaesthesia was induced with propofol (bolus of 2.5 mg . kg-1, fo
llowed by a continuous infusion of 10 mg . kg-1 . h-1) and vecuronium
(0.1 mg . kg-1). Heart rate and mean arterial pressure were assessed n
on-invasively before and after induction of anaesthesia and immediatel
y after tube or laryngeal mask insertion. Orotracheal intubation elici
ted a significant increase in heart rate (92 +/- 16 vs 77 +/- 19 b . m
in-1, p < 0.05) and in mean arterial pressure (117 +/- 21 vs 85 +/- 16
mmHg, p < 0.05), whereas there was significant increase in heart rate
(74 +/- 11 vs 72 +/- 12 b . min-1) and mean arterial pressure (86 +/-
8 vs 81 +/- 10 mmHg) after insertion of the laryngeal mask. In both g
roups, plasma catecholamine concentrations were not significantly modi
fied after tube or laryngeal mask insertion. It is concluded that, und
er propofol anaesthesia, laryngeal mask insertion does not induce any
significant haemodynamic response in ASA 1 patients. In the opposite,
orotracheal intubation increases both heart rate and mean arterial pre
ssure.