Objective: To evaluate the incidence, associated factors and gravity o
f self-extubations. Design: Prospective study about all patients intub
ated over an 8 month period. Setting: A medical intensive care unit of
a University Hospital Patients: Patients were divided into two groups
: self-extubated and those that did not. The self-extubations were sep
arated into deliberate acts by the patients and accidental. Results: 2
4 of the 197 patients included presented a total of 27 extubations (12
%). There were 21 deliberate incidents and 6 accidental. The only diff
erences between the cases and the rest of the population were a higher
mean age (67 vs 59 years) and a larger proportion of chronic respirat
ory failure (66% versus 35%). Reintubation was necessary in 20 cases (
74%) within 30 min in 16 cases. The main indication for reintubation w
as acute respiratory distress (90%). Reintubation was associated with
one death. Conclusion: Self-extubation is a frequent and serious compl
ication of mechanical ventilation. Deliberate self-extubation, the mos
t frequent type of incident could possibly be reduced by better sedati
on of agitated patients and accidental self-extubation by better train
ing of the nursing staff.