Vulnerability of brain tissue against ischemia limits the success of c
ardiopulmonary resuscitation. Promising therapeutic results in animal
studies are not accompanied by conclusive clinical concepts of success
full cerebral resuscitation. Zwenty-five% of ischemic strokes are due
to cardiogenic embolism. In the elderly atrial fibrillation is the mos
t common source of cardiogenic embolism. After embolic stroke the use
of early anticoagulation with heparin is not definitely proven, but th
e risk of parenchymatous hemorrhage is lower than it was feared earlie
r. An American study suggests a possible role for less intense oral pr
ophylactic anticoagulation with coumarins. There is a frequent associa
tion between central nervous system symptoms and infective endocarditi
s.