H. Boisseau et al., STUDY OF FLUORESCENT-ANTIBODIES DIRECTED AGAINST THE GUT EPITHELIUM OF SCHISTOSOMA-MANSONI .5. EGG GRANULOMA MODULATION BY AN IGM MONOCLONAL-ANTIBODY, Annales de Parasitologie humaine et comparee, 68(3), 1993, pp. 115-120
The periovular granulomatous reaction has been reduced in vivo by an I
gM monoclonal antibody. The granulomatous reaction has been obtained e
ither in unsensitized, or sensitized as well as immunized mouse. The g
ranulomatous reduction could be explained by a decrease in egg viabili
ty, owing to the fact that the monoclonal antibody is lethal against a
n in vitro miracidium suspension.