STEREOCONTROLLED SYNTHESIS OF CYCLIC ETHERS BY INTRAMOLECULAR HETERO-MICHAEL ADDITION .3. ENANTIOMERIC SYNTHESIS OF HIGHLY FUNCTIONALIZED AND FUSED TETRAHYDROPYRANS
Jm. Palazon et al., STEREOCONTROLLED SYNTHESIS OF CYCLIC ETHERS BY INTRAMOLECULAR HETERO-MICHAEL ADDITION .3. ENANTIOMERIC SYNTHESIS OF HIGHLY FUNCTIONALIZED AND FUSED TETRAHYDROPYRANS, Tetrahedron letters, 34(34), 1993, pp. 5467-5470
A methodology based on intramolecular hetero-Michael addition of prope
rly functionalized alkoxy-gamma-benzoyloxy-alpha,beta-unsaturated este
rs for the synthesis of highly substituted and fused poly-tetrahydropy
ran nuclei of marine polyether toxins with absolute control of all the
stereocentres is described.