THE STOCHASTIC SI MODEL WITH RECRUITMENT AND DEATHS .1. COMPARISON WITH THE CLOSED SIS MODEL

Citation
Ja. Jacquez et Cp. Simon, THE STOCHASTIC SI MODEL WITH RECRUITMENT AND DEATHS .1. COMPARISON WITH THE CLOSED SIS MODEL, Mathematical biosciences, 117(1-2), 1993, pp. 77-125
Citations number
25
Categorie Soggetti
Mathematical Methods, Biology & Medicine","Mathematics, Miscellaneous","Biology Miscellaneous
Journal title
ISSN journal
00255564
Volume
117
Issue
1-2
Year of publication
1993
Pages
77 - 125
Database
ISI
SICI code
0025-5564(1993)117:1-2<77:TSSMWR>2.0.ZU;2-J
Abstract
We compare the stochastic and deterministic versions of an SI model wi th recruitment, background deaths, and deaths due to the disease. For the stochastic version, analysis of the mean number of susceptibles, m (X), and infecteds, m(Y), and of the means conditioned on nonextinctio n of the infection, m(X) and m(Y)*, shows that (1) if R0 less-than-or -equal-to 1, the disease dies out monotonically for the deterministic and stochastic models, and (2) if R0 > 1, the disease dies out early w ith a probability close to (1/R0)a, where a is the number of infecteds introduced, or m(Y) rises to a peak and then dies out slowly. For sma ll populations N, the peak is an obvious maximum. If N greater-than-or -equal-to 100, the peak in m(Y) is hidden in a long, nearly stationary plateau and m(Y) is close to the deterministic endemic level for a l arge range of parameter values. The analytical results are illustrated with simulations. The results for the SI model are motivated by and c ompared with the corresponding results for the closed SIS model.