INTERACTION BETWEEN DIVERSE SYNTHETIC POL YPEPTIDES IN AQUEOUS-SOLUTION

Inferaction between water soluble diverse, synthetic, polypeptides in aqueous solution was studied by circular dichroism (CD) spectra. The i nteraction was evaluated from the significant difference between minim um of maximum peaks of CD spectra in ellipticity for mixed solution of two peptides and mean ellipticity of the each peptide. The minimum pe ak of a mixture for poly(Ala, Pro) ; A with Poly(Ala, Asp) ; B, or Pol y(Ala, Lys) ; C, respectively, was less than the mean value of those o f A and B or A and C. The minimum peak of polyproline ; D with B was l ess than the mean value of that of D with C. While, the CD pattern of the mixture of poly(Ala, Asp) ; A, with poly(Gly, Pro) ; E or poly(Ala , DL-Trp) ; F, respectively, was accordance with average of those A an d E or A and F.