OBJECTIVE - To assess in diabetic subjects the effects of dietary sucr
ose on glycemia and lipemia. RESEARCH DESIGN AND METHODS- Twelve type
II diabetic subjects consumed, in random order, two isocaloric, 55% ca
rbohydrate study diets for 28 days. In one diet, 19% of energy was der
ived from sucrose. In the other diet, <3% of energy was derived from s
ucrose, and carbohydrate energy came primarily from starch. Both study
diets were composed of common foods. All meals were prepared in a met
abolic kitchen where foods were weighed during meal preparation. RESUL
TS - No significant differences were noted between the study diets at
any time point in mean plasma glucose. At day 28, mean plasma glucose
values for the sucrose diet were 9.6 +/- 0.5 mM and for the starch die
t were 9.4 +/- 0.6 mM (P = 0.63). Also, no significant differences wer
e observed between the study diets in urine glucose; fasting serum tot
al, HDL, or LDL cholesterol; fasting serum TG; or peak postprandial se
rum TG. CONClUSIONS - A high sucrose diet did not adversely affect gly
cemia or lipemia in type II diabetic subjects.