The adequate stimuli for taste receptors on the legs of tsetse flies (
Glossina spp.) have hitherto been unknown. Here we present electrophys
iological evidence that for Glossina fuscipes fuscipes human sweat-man
is one of the flies' hosts-is an adequate stimulus. The receptor cell
s which respond to human sweat are located in two sensilla proximal to
the base of the empodium at the distal end of the fifth tarsomere. Th
e receptors are sensitive to four of the 14 major components of sweat
tested: uric acid, leucine, valine and lactic acid. We show that flies
display more feeding behaviour on surfaces treated with sweat, uric a
cid, leucine or valine than on untreated surfaces.