ANCISTROBREVINE-C FROM ANCISTROCLADUS-ABBREVIATUS - THE 1ST MIXED ANCISTROCLADACEAE DIONCOPHYLLACEAE-TYPE NAPHTHYLISOQUINOLINE ALKALOID

The isolation of a new naphthylisoquinoline alkaloid, ancistrobrevine C, from the stem bark and the roots of Ancistrocladus abbreviatus is d escribed. Its complete structure was established by spectroscopic, chi roptical and degradative methods. For additional structural confirmati on, the new alkaloid was transformed into ent-ancistrocladisine, a ste reochemically well known naphthylisoquinoline. Accordingly, ancistrobr evine C is neither a real Ancistrocladaceae- nor a true Dioncophyllace ae-type alkaloid, but the first mixed, hybrid-like naphthylisoquinolin e alkaloid.