EXTRAORDINARY DIASTEREOSELECTIVITY COUPLED TO ALTERED STRUCTURE OF DIPEPTIDE ESTERS

Authors
MATSUMOTO Y MATSUMOTO Y INOUE J UEOKA R
Citation
Y. Matsumoto et al., EXTRAORDINARY DIASTEREOSELECTIVITY COUPLED TO ALTERED STRUCTURE OF DIPEPTIDE ESTERS, Chemistry Letters, (8), 1993, pp. 1303-1304
Citations number
5
Categorie Soggetti
Chemistry
Journal title
Chemistry Letters → ACNP
ISSN journal
03667022
Issue
8
Year of publication
1993
Pages
1303 - 1304
Database
ISI
SICI code
0366-7022(1993):8<1303:EDCTAS>2.0.ZU;2-X
Abstract
The diastereoselectivity for the hydrolysis of Z-D(L)-Phe-L-Phe p-meth oxy-carbonylphenyl ester was maximized (k(S)DL/k(S)LL = 34) at the opt imum temperature (30-degrees-C). This could be attributed to the confo rmational change in the DL isomer, which was supported by the circular dichroism measurements.