AN ADDITIONAL LOCUS (PI4) IN THE PROTEASE INHIBITOR (PI) GENE-CLUSTEROF PIGS

Authors
CIZOVA D GABRISOVA E STRATIL A HOJNY J
Citation
D. Cizova et al., AN ADDITIONAL LOCUS (PI4) IN THE PROTEASE INHIBITOR (PI) GENE-CLUSTEROF PIGS, Animal genetics, 24(4), 1993, pp. 315-318
Citations number
11
Categorie Soggetti
Genetics & Heredity","Veterinary Sciences
Journal title
Animal genetics → ACNP
ISSN journal
02689146
Volume
24
Issue
4
Year of publication
1993
Pages
315 - 318
Database
ISI
SICI code
0268-9146(1993)24:4<315:AAL(IT>2.0.ZU;2-8
Abstract
A further alpha-protease inhibitor system, PI4, was detected in porcin e sera using either 2D agarose gel, pH 5.0-PAGE, pH 9.0, or 1D PAGE fo llowed by immunoblotting with rabbit anti-porcine PI2 or PI3 antisera. PI4 inhibited chymotrypsin, but not trypsin. Seven allelic variants o f PI4 were described. By haplotyping of alpha-protease inhibitor syste ms in 52 complete families it was shown that PI4 locus belongs to the PI gene cluster. The probable order of the PIloci was: PI1, PO1A, PI2, PI4, PI3.