STRUCTURES AND SOLID-STATE TAUTOMERIC FORMS OF 2 NOVEL ANTILEUKEMIC TROPOLOISOQUINOLINE ALKALOIDS, PAREIRUBRINE-A AND PAREIRUBRINE-B, FROM CISSAMPELOS-PAREIRA

Authors
MORITA H MATSUMOTO K TAKEYA K ITOKAWA H IITAKA Y
Citation
H. Morita et al., STRUCTURES AND SOLID-STATE TAUTOMERIC FORMS OF 2 NOVEL ANTILEUKEMIC TROPOLOISOQUINOLINE ALKALOIDS, PAREIRUBRINE-A AND PAREIRUBRINE-B, FROM CISSAMPELOS-PAREIRA, Chemical and Pharmaceutical Bulletin, 41(8), 1993, pp. 1418-1422
Citations number
10
Categorie Soggetti
Pharmacology & Pharmacy",Chemistry
Journal title
Chemical and Pharmaceutical Bulletin → ACNP
ISSN journal
00092363
Volume
41
Issue
8
Year of publication
1993
Pages
1418 - 1422
Database
ISI
SICI code
0009-2363(1993)41:8<1418:SASTFO>2.0.ZU;2-A
Abstract
Two novel tropoloisoquinoline alkaloids, Pareirubrines A and B, have b een isolated as antileukemic substances from Cissampelos pareira (Meni spermaceae), together with the same skeleton alkaloids, grandirubrine and isoimerubrine. Their structures were elucidated by nuclear magneti c resonance (NMR) studies, and their solid state tautomeric forms were examined by X-ray crystallographic analysis.