1,3-PHOSPHOROTROPIC REARRANGEMENT OF PYRIDYL PHOSPHATES TO HYDROXYPYRIDYL PHOSPHONATES

Authors
ONYSKO PP SUVALOVA EA CHUDAKOVA TI SINITSA AD
Citation
Pp. Onysko et al., 1,3-PHOSPHOROTROPIC REARRANGEMENT OF PYRIDYL PHOSPHATES TO HYDROXYPYRIDYL PHOSPHONATES, Heteroatom chemistry, 4(4), 1993, pp. 361-364
Citations number
20
Categorie Soggetti
Chemistry
Journal title
Heteroatom chemistry → ACNP
ISSN journal
10427163
Volume
4
Issue
4
Year of publication
1993
Pages
361 - 364
Database
ISI
SICI code
1042-7163(1993)4:4<361:1ROPPT>2.0.ZU;2-U
Abstract
The lithium diisopropylamide (LDA) induced regioselective 1,3-rearrang ement of 3- and 2- pyridyl phosphates into the corresponding 3-hydroxy -4-pyridyl- and 2-hydroxy-3-pyridylphosphonates has been observed and investigated. The rearrangement is proposed as a useful method for a d irected introduction of a phosphoryl group into a hydroxypyridine nucl eus.