STUDY ON MEMBRANE-PERMEABILITY OF CITELLU S-UNDULATUS ERYTHROCYTES UNDER CONDITIONS OF HYPOTHERMIC STORAGE

We have studied the influence of the erythrocyte hypothermic storage o f long-tailed ground squirrels at various physiological states and whi le mongrel rats on the impairment of the barrier function of their mem branes for ferricyanide. The membranes of sleeping and awakening groun d squirrels demonstrate the highest stability (the structural integrit y is sustained for 3-3,5 months), meanwhile rat blood erythrocytes mai ntaine the barrier function only for 2 weeks. Beside structural and vi scosal changes in the erythrocyte membrane and the cytosole of hiberna ting ground squirrel an important role in maintaining barrier function under conditions of hypothermic storage is played by the content of a nimal blood plasm. Appearence of a non-typical EPR spin probe spectrum in some ground squirrel blood samples in non-equilibrium state of ent ering or arrousing from hibernation has been observed.