L. Marpeau et al., INTRAVENOUS SULPROSTONE AND UTERINE SCARRING BASED UPON 22 CASES OF THERAPEUTIC-ABORTION DURING 2ND AND 3RD TRIMESTERS OF PREGNANCY, European journal of obstetrics, gynecology, and reproductive biology, 50(2), 1993, pp. 105-108
A preliminary study in 22 patients with uterine scarring was undertake
n using sulprostone by intravenous infusion when therapeutic abortion
was deemed necessary during the 2nd and 3rd trimesters of pregnancy. T
he dosage used was 500 mug by slow infusion lasting 10 h. There were n
o cases of ruptured uterus. Adverse reactions were absent. Results wer
e satisfactory. Mean induction-expulsion duration: 11 h. Expulsion rat
e in 24 h: 63%. With strict monitoring and in a specialized center, th
is technique may be suggested when a late therapeutic abortion with a
scarred uterus is indicated.