LIPID-MEMBRANE STRUCTURE AND DYNAMICS STUDIED BY ALL-ATOM MOLECULAR-DYNAMICS SIMULATIONS OF HYDRATED PHOSPHOLIPID-BILAYERS

Authors
STOUCH TR
Citation
Tr. Stouch, LIPID-MEMBRANE STRUCTURE AND DYNAMICS STUDIED BY ALL-ATOM MOLECULAR-DYNAMICS SIMULATIONS OF HYDRATED PHOSPHOLIPID-BILAYERS, Molecular simulation, 10(2-6), 1993, pp. 335
Citations number
110
Categorie Soggetti
Physics, Atomic, Molecular & Chemical
Journal title
Molecular simulation → ACNP
ISSN journal
08927022
Volume
10
Issue
2-6
Year of publication
1993
Database
ISI
SICI code
0892-7022(1993)10:2-6<335:LSADSB>2.0.ZU;2-7
Abstract
The structure and dynamics of phosphatidylcholine bilayers are examine d by reviewing the results of several nanoseconds of molecular dynamic s simulations on a number of bilayer and monolayer models. The lengths of these simulations, the longest single one of which was 2 nanosecon ds, were sufficiently long to effectively sample many of the longer-sc ale motions governing the behaviour of biomembranes. These simulations reproduce many experimental observables well and provide a degree of resolution currently unavailable experimentally.