ALKYLATION REACTIONS BY MEANS OF ALKANOLS AND CARBON-MONOXIDE - AN EFFICIENT SYNTHESIS OF THIOETHERS AND OF CAFFEINE FROM THEOPHYLLINE

Authors
BOTT K
Citation
K. Bott, ALKYLATION REACTIONS BY MEANS OF ALKANOLS AND CARBON-MONOXIDE - AN EFFICIENT SYNTHESIS OF THIOETHERS AND OF CAFFEINE FROM THEOPHYLLINE, Chemische Berichte, 126(8), 1993, pp. 1955-1956
Citations number
7
Categorie Soggetti
Chemistry
Journal title
Chemische Berichte → ACNP
ISSN journal
00092940
Volume
126
Issue
8
Year of publication
1993
Pages
1955 - 1956
Database
ISI
SICI code
0009-2940(1993)126:8<1955:ARBMOA>2.0.ZU;2-U
Abstract
The reaction of sodium or potassium thialates with alkanols and carbon monoxide provides a versatile route to produce thioethers in excellen t yields. By analogy, the potassium salt of theophylline suffers a nea rly quantitative conversion to caffeine when heated with methanol unde r CO pressure. The mechanism of these alkylation reactions is discusse d.