EARLY CLINICAL-EXPERIENCES IN TUMOR-DIAGN OSIS WITH RADIOACTIVE LANTHANIDE COMPLEXES

Clinical investigations have been made in 70 patients to determine whe ther Yb-169-labelled metal ligand complexes accumulate in various tumo rs as was shown by previous animal experiments. The time course of the se radiopharmaceuticals in tumors, the skeleton and the liver permitte d a good to excellent tumor imaging in 61/70 cases. Even 2-5 h after i ntravenous injection of the radioactive compound, a meaningful diagnos is could be made in the majority of cases. A number of lesions were fo und for which no equivalent findings were available with other methods . They were therefore interpreted as metastases.