Fine needle aspiration or biopsy is used for cytologic diagnosis of ma
ny intra-abdominal tumors including focal liver lesions. The incidence
of needle tract seeding is quite low. In this paper the first case of
cutaneous seeding after percutaneous fine needle aspiration of liver
metastasis is reported in a case of colon cancer. We suggest using thi
s method for cytologic diagnosis in hepatic tumors when surgical resec
tion is not possible and when patients will be treated with invasive t
herapies and to avoid fine needle aspiration biopsy in patients underg
oing surgical resection or when there is a confident diagnosis of HCC
by non-invasive procedures.