THERAPY WITH ANTIBIOTICS IN PREGNANCY

Antibiotics are the most frequently prescribed medications in pregnanc y, their application and choice should be made according to the highes t criteria. Penicillins and cephalosporins can be safely used in pregn ancy, however, their side effects such as allergic reactions present a greater therapeutic problem. Tetracyclines, chloramphenicol and quino lones are strictly contraindicated in pregnancy. 5-nitroimidazole deri vatives, aminoglycosides and sulfonamides are indicated only in severe infections. Not only the risk of malformation is increased in the emb ryonic stage, i.e. in the first 8 weeks of gestation, but also at the time of delivery with the use of drugs as sulfonamides, which can caus e icterus.