IS LUNG-CANCER RESECTION JUSTIFIED IN PATIENTS AGED OVER 70 YEARS

Citation
P. Thomas et al., IS LUNG-CANCER RESECTION JUSTIFIED IN PATIENTS AGED OVER 70 YEARS, European journal of cardio-thoracic surgery, 7(5), 1993, pp. 246-250
Citations number
NO
Categorie Soggetti
Cardiac & Cardiovascular System
ISSN journal
10107940
Volume
7
Issue
5
Year of publication
1993
Pages
246 - 250
Database
ISI
SICI code
1010-7940(1993)7:5<246:ILRJIP>2.0.ZU;2-O
Abstract
From January 1980 through January 1985, 452 consecutive patients under went pulmonary resection for primary non-small cell bronchogenic cance r. Forty-seven patients (10.4%) were 70 years old or older: there were 45 men and 2 women, with a mean age of 72.4 years (S.D.: 2.6; range: 70-79). This population was comparable to the 405 younger patients wit h respect to the type of resection, histology and TNM staging. Whereas the non-fatal complication rate was similar in both groups (25.5% ver sus 29.9%), the in-hospital mortality rate was significantly higher in the older patients (12.8% versus 4.7%; P less-than-or-equal-to 0.05). The mortality rate after extended resections was significantly higher among the older patients (33.3% versus 6%, P less-than-or-equal-to 0. 01). The cause of death was myocardial infarction in half the cases; t he underlying coronary disease was unrecognized preoperatively in one- third. Five-year survival was comparable in both groups: 29.8% and 33% , respectively. We conclude that pulmonary resection for bronchogenic cancer is justified in patients over 70 years; a careful preoperative assessment ought to be performed and standard resections should be pre ferred.