Background. Genital human papillomavirus (HPV) infection is one of the
most common sexually transmitted diseases, and it has been identified
as a significant risk factor for the development of dysplasia and can
cer of the uterine cervix. The possible influence of male HPV lesions
on female cervix oncogenesis has not been elucidated so far. In the pr
esent study we evaluate the male partners of women with clinical or su
bclinical Hpv infection with particular interest in the clinical featu
res of this infection in both partners. Methods. We examined 81 male p
artners of women affected with human papillomavirus infections. Condyl
omata acuminata were searched for by visual inspection. Subclinical le
sions were searched by 5 power optical magnification lens after applic
ation of 5% acetic acid. Results. In men we observed the following per
centage of infection: 67% of the partners of women affected with condy
lomata acuminata, 46% of the partners of women affected with subclinic
al lesions (acetic acid positive), and 40% of the partners of women wi
th association Of HPV and cervical intraepithelial neoplasia. Conclusi
ons. Our data stress that very often the partners of women with HPV su
bclinical infection, especially when associated with CIN, do not prese
nt lesions, and consequently primary prevention may be very difficult.