Jg. Gaertner et P. Dhurjati, SPECIFIC CELL-ADHESION AS POTENTIAL CAUSE OF INTERACTIONS BETWEEN HYBRIDOMA CELLS AND REACTOR SURFACES, Biotechnology letters, 15(8), 1993, pp. 803-808
Hybridoma cells grown in the presence of different reactor surfaces we
re affected by the reactor surface properties. Cell growth rate and ce
ll attachment were affected differently. To explain this observed effe
ct a mechanism involving specific adhesion (mediated by fibronectin) o
f the cells to the reactor surfaces was proposed and tested.