At. Evans et al., COMPARISON OF PENTOBARBITAL ALONE AND PENTOBARBITAL IN COMBINATION WITH LIDOCAINE FOR EUTHANASIA OF DOGS, Journal of the American Veterinary Medical Association, 203(5), 1993, pp. 664-666
Pentobarbital alone, pentobarbital plus 1% lidocaine solution, pentoba
rbital plus 2% lidocaine solution, and pentobarbital plus 3% lidocaine
solution were each used to euthanatize 6 dogs. For each dog, time bet
ween the beginning of injection of the euthanasia solution and each of
the following events was recorded: collapse, onset of apnea, flat-lin
e electrocardiogram, flat-line electroencephalogram, loss of palpable
heartbeat, and loss of palpable pulse. Any signs of pain or discomfort
were also recorded. There were no significant differences among group
s except for time to flat-line electrocardiogram. Dogs euthanatized wi
th pentobarbital alone had significantly longer times than did dogs eu
thanatized with pentobarbital in combination with any of the lidocaine
concentrations. We concluded that pentobarbital in combination with l
idocaine was a reasonable alternative to pentobarbital alone when euth
anatizing dogs.