A. Gogus et al., RECONSTRUCTION OF THE CRUCIATE LIGAMENTS WITH ALLOGRAFTS - CLINICAL PERSPECTIVE AND SHORT-TERM RESULTS, Der Unfallchirurg, 96(2), 1993, pp. 93-99
There is a continuing search for the ideal substitute for the cruciate
ligaments. Autogenous tissues have been widely used as a replacement.
The use of allografts is an attractive alternative: no donor side mor
bidity, decreased operative time, smaller incisions, especially with n
ew endoscopic techniques, unlimited supply with a choice of graft size
s in multiple ligament reconstructions and a long shelf-life are some
of the distinct advantages that allografts offer. They may be useful i
n circumstances where there is no suitable autologous substitute or th
e available tendon is too short to span the joint cavity. The preparat
ion of an allograft requires appropriate donor selection and screening
, careful surgical tissue procurement, and safe and effective processi
ng techniques. At the present time, the issue of secondary sterilizati
on of allografts remains controversial. Subclinical immune response an
d the possibility of transmission of infectious agents have to be cons
idered. The early results in the literature and in our small series ar
e encouraging; however, long-term results are necessary prior to wides
pread use of allografts in cruciate ligaments reconstructions. The aut
hors believe that allografts should presently be reserved for use as a
n alternative to prosthetic ligaments in situations where autografts a
re unavailable or inappropriate.