SYNTHESIS OF AN ENANTIOMERICALLY PURE INTERMEDIATE CONTAINING THE CD SUBSTRUCTURE OF TAXOL

Authors
ISAACS RCA DIGRANDI MJ DANISHEFSKY SJ
Citation
Rca. Isaacs et al., SYNTHESIS OF AN ENANTIOMERICALLY PURE INTERMEDIATE CONTAINING THE CD SUBSTRUCTURE OF TAXOL, Journal of organic chemistry, 58(15), 1993, pp. 3938-3941
Citations number
19
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of organic chemistry → ACNP
ISSN journal
00223263
Volume
58
Issue
15
Year of publication
1993
Pages
3938 - 3941
Database
ISI
SICI code
0022-3263(1993)58:15<3938:SOAEPI>2.0.ZU;2-5
Abstract
A straightforward conversion of the (R)-(-)-Hajos-Parrish ketone 5 to oxetane 13 is reported. It is anticipated that intermediates related t o this compound could be useful for the total synthesis of taxol.