PICHIA-ANOMALA KILLER TOXIN SECRETION IN THE PRESENCE OF TUNICAMYCIN

Authors
CAILLIEZ JC CANTELLI C CONTI S GERLONI M MAGLIANI W MORACE G POLONELLI L
Citation
Jc. Cailliez et al., PICHIA-ANOMALA KILLER TOXIN SECRETION IN THE PRESENCE OF TUNICAMYCIN, Journal of medical and veterinary mycology, 31(4), 1993, pp. 337-342
Citations number
24
Categorie Soggetti
Mycology
Journal title
Journal of medical and veterinary mycology → ACNP
ISSN journal
02681218
Volume
31
Issue
4
Year of publication
1993
Pages
337 - 342
Database
ISI
SICI code
0268-1218(1993)31:4<337:PKTSIT>2.0.ZU;2-1
Abstract
The role of N-glycosylation in the secretion and activity of a Pichia anomala killer toxin was studied using tunicamycin. Secretion of the y east toxin was localized using a specific monoclonal antibody. Preserv ation of the toxin killer effect was evaluated with two sensitive yeas t strains. Tunicamycin did not affect the secretion of active toxin, s uggesting that N-glycosylation does not appear to be involved in eithe r toxin secretion or in killer activity.