MULTIVALENT VACCINES - PROSPECTS AND CHALLENGES

The advantages and disadvantages of combination vaccines are set out w ith a clear indication that, although there are many (described and di scussed) influences on in the immunogenicity of a vaccine it would sti ll be of considerable value to be able to deliver such materials with the minimum number of needle-stick injections. Such a situation may be come facilitated in the future as vaccines based on plasmid DNA become available; a prospect which is examined in outline in the final secti on.