The clinical application of two-dimensional contrast echocardiography
to pericardiocentesis was investigated in 20 patients with pericardial
effusion. Multiple views were obtained to determine the ideal needle
entry route. During pericardiocentesis, after 5 to 10 mL of pericardia
l fluid was withdrawn, 3 to 5 mL of agitated saline solution was injec
ted through the exploring needle into the pericardium and a cloud of e
choes indicated the needle's position. Contrast echoes were observed i
n all 20 patients. The procedure was performed smoothly in all patient
s except two (10%): the exploring needle was inserted into the right a
trium in one patient and into the right ventricle in the other patient
. The former promptly underwent a surgical drainage procedure, and the
latter a second pericardiocentesis successfully guided by contrast ec
hocardiography. The pericardial fluid was simply, safely, and successf
ully aspirated in the other 18 patients. We conclude that two-dimensio
nal contrast echocardiography is valuable for locating needle position
, thus facilitating successful pericardiocentesis in clinical practice
.