This paper presents two new rebinning algorithms for the reconstructio
n of three-dimensional (3-D) positron emission tomography (PET) data,
A rebinning algorithm is one that first sorts the 3-D data into an ord
inary two-dimensional (2-D) data set containing one sinogram for each
transaxial slice to be reconstructed; the 3-D image is then recovered
by applying to each slice a 2-D reconstruction method such as filtered
-backprojection, This approach allows a significant speedup of 3-D rec
onstruction, which is particularly useful for applications involving d
ynamic acquisitions or whole-body imaging, The first new algorithm is
obtained by discretizing an exact analytical inversion formula, The se
cond algorithm, called the Fourier rebinning algorithm (FORE), is appr
oximate but allows an efficient implementation based on taking 2-D Fou
rier transforms of the data, This second algorithm was implemented and
applied to data acquired with the new generation of PET systems and a
lso to simulated data for a scanner with an 18 degrees axial aperture,
The reconstructed images were compared to those obtained with the 3-D
reprojection algorithm (3DRP) which is the standard ''exact'' 3-D fil
tered-backprojection method, Results demonstrate that FORE provides a
reliable alternative to 3DRP, while at the same time achieving an orde
r of magnitude reduction in processing time.