MAPPING OF 59 EST GENE MARKERS IN 31 INTERVALS SPANNING THE HUMAN X-CHROMOSOME

Authors
GIANFRANCESCO F ESPOSITO T RUINI L HOULGATTE R NAGARAJA R DESPOSITO M ROCCHI M AUFFRAY C SCHLESSINGER D DURSO M FORABOSCO A
Citation
F. Gianfrancesco et al., MAPPING OF 59 EST GENE MARKERS IN 31 INTERVALS SPANNING THE HUMAN X-CHROMOSOME, Gene, 187(2), 1997, pp. 179-184
Citations number
26
Categorie Soggetti
Genetics & Heredity
Journal title
Gene → ACNP
ISSN journal
03781119
Volume
187
Issue
2
Year of publication
1997
Pages
179 - 184
Database
ISI
SICI code
0378-1119(1997)187:2<179:MO5EGM>2.0.ZU;2-2
Abstract
The positioning of Expressed Sequence Tags (ESTs) constitutes an impor tant step towards a functional map of the human genome, including cand idate genes for human genetic disorders that have been localized by li nkage analysis. We localized 59 ESTs on the human X chromosome, includ ing 44 derived from infant brain and 15 from adult muscle cDNA librari es. Localizations by a somatic cell hybrid panel were refined for five cDNAs by mapping them in yeast artificial chromosome (YAC) contigs.