ASSESSMENT OF LEFT-VENTRICULAR EJECTION FRACTION FROM TECHNETIUM-99M-METHOXY ISOBUTYL ISONITRILE MULTIPLE-GATED RADIONUCLIDE ANGIOCARDIOGRAPHY

Abnormal left ventricular function is a diagnostic indication of cardi ac disease. Left ventricular function is commonly quantified by ejecti on fraction measurements. A novel approach for the determination of le ft ventricular ejection fraction from technetium-99m-methoxy isobutyl isonitrile multiple-gated radionuclide angiocardiography is presented. Data from 23 patients, symptomatic of cardiac disease, indicate that ejection fractions determined using the radionuclide technique correla te well with contrast X-ray single-plane cineangiography (r = 0.83, p < 10(-6)). Data from 14 of the patients indicate favorable correlation with technetium-99m-pertechnetate gated blood pool radionuclide angio cardiography (r = 0.87, p < 10(-4)).