STEROIDS .52. CONFIGURATIONAL ANALYSIS OF 16-METHYL-19-NORTESTOSTERONE DERIVATIVES

Authors
MESKO E DOMBI G LUKACS F SCHNEIDER G
Citation
E. Mesko et al., STEROIDS .52. CONFIGURATIONAL ANALYSIS OF 16-METHYL-19-NORTESTOSTERONE DERIVATIVES, Liebigs Annalen der Chemie, (8), 1993, pp. 923-925
Citations number
20
Categorie Soggetti
Chemistry
Journal title
Liebigs Annalen der Chemie → ACNP
ISSN journal
01702041
Issue
8
Year of publication
1993
Pages
923 - 925
Database
ISI
SICI code
0170-2041(1993):8<923:S.CAO1>2.0.ZU;2-I
Abstract
The four possible stereoisomers of 3-methoxy-16-methyloe-stra-1,3,5(10 )-trien-17-ol (1, 2, 3, 4) were converted into the corresponding 16-me thyl-19-nortestosterone analogs (5, 6, 7, 8), which were characterized by their H-1- and C-13-NMR spectra. The coupling constants J16,17 and the characteristic C-13 signals (C-12, C-17, C-18, 16-CH3) clearly co nfirmed the configurations at C-16 and C-17.