cDNA encoding alpha-class glutathione S-transferase Yc (GSTYc) has bee
n isolated from a Syrian hamster kidney library, and its nucleotide se
quence (968 bp) has been determined. Analysis of the deduced amino aci
d sequence revealed a high level of identity between Syrian hamster GS
TYc, rat GST Yc1 and Yc2 and mouse GSTYc. Northern-blot experiments de
monstrated that Syrian hamster GSTYc expression is tissue-specific. A
GSTYc mRNA of approx. 1 kb is expressed in liver, kidney, vas deferens
and epididymis. Expression of the GSTYc transcript was not detected i
n testis or uterus.