Objectives. The objectives of this study were to 1) define the inciden
ce of syncope coming to medical attention among children and adolescen
ts, 2) determine the outcome of syncope in these patients, and 3) dete
rmine changes over time in the evaluation and charges for evaluating t
his problem. Background. Syncope occurs commonly in children and adole
s cents. However, the mid- and long-term outcome of children and adole
scents who experience syncope is unknown. Methods. Utilizing the Roche
ster Epidemiology Project, we determined the incidence, outcome and ch
arges for medical evaluation for patients seeking medical attention fo
r syncope during an early 5-year period (1950 to 1954) and a more rece
nt 5-year period (1987 to 1991). Results. The incidence of syncope com
ing to medical attention was 71.9 and 125.8/100,000 population for the
early and more recent cohort, respectively. The incidence was higher
for female than for male patients. The incidence peaked in 15- to 19-y
ear old patients. Acute illness and noxious stimuli were associated wi
th 24% and 23% of the episodes, respectively. Although long-term survi
val was not different from that of the general population, one child d
ied suddenly, and another had hereditary prolonged QT interval syndrom
e. These were two of only six patients who had exertional syncope. Tot
al charges for evaluation of syncope were similar in the two time peri
ods. However, charges for testing procedures were greater for the more
recent cohort. Conclusions. In general, syncope in children and adole
scents is a benign event. Syncope occurring during exercise may identi
fy patients with a potentially fatal condition. Detailed evaluation sh
ould be considered for patients who have syncope during exercise or wh
o have a family history of syncope, sudden death, myocardial disease o
r arrhythmias. It may be prudent to obtain an electrocardiogram for al
l patients who seek medical attention for syncope. (C)1997 by the Amer
ican College of Cardiology.