EFFECTS OF REPEATED APPLICATION OF EMOLLIENT CREAM TO PREMATURE NEONATES SKIN

Objective. Emollient cream moisturizers are often used on premature ne wborns in neonatal intensive care units without accurate knowledge of the risks or benefits to the neonate. Design. We prospectively compare d premature neonates treated with a water-in-oil emollient cream for u p to 16 days to untreated premature neonates. Setting. The study was c ompleted in a neonatal intensive care unit on neonates admitted for re spiratory distress and/or possible sepsis. Patients. Thirty-four neona tes, between 29 and 36 weeks estimated gestational age, entered the st udy. Interventions. One-half of the neonates were treated twice a day with an water-in-oil emollient cream, and the other half served as con trols. Outcome Measures. The skin condition of the neonates' hands, fe et, and abdomen was evaluated on entering the study and twice a week. Fungal cultures and quantitative bacterial cultures were obtained from the axilla and abdomen on entering the study and twice a week. Result s. The mean gestational age of the treated neonates was 32.3 weeks, wh ereas the mean gestational age of the control neonates was 32.5 weeks. The neonates treated with emollient cream demonstrated statistically less dermatitis of their hands (day 2 through day 11), their feet (day 2 through day 16), and their abdomen (day 7 through day 11). Fungal c ultures and quantitative bacterial cultures of the abdomen and axilla were equivalent in both groups. Conclusions. These studies document th at emollient cream moisturizer therapy of premature neonates decreases dermatitis without changing the microbiological flora.