IDENTIFICATION OF A NUCLEAR RETINOIC ACID-BINDING ACTIVITY REPRESENTATIVE OF ENDOGENEOUS RETINOIC ACID RECEPTORS IN THE NUCLEI OF RAT-LIVERAND TESTIS

Authors
MANO H KUMAKURA C KITAMURA A MORINO H KATO S MASUSHIGE S
Citation
H. Mano et al., IDENTIFICATION OF A NUCLEAR RETINOIC ACID-BINDING ACTIVITY REPRESENTATIVE OF ENDOGENEOUS RETINOIC ACID RECEPTORS IN THE NUCLEI OF RAT-LIVERAND TESTIS, Bioscience, biotechnology, and biochemistry, 57(8), 1993, pp. 1400-1402
Citations number
12
Categorie Soggetti
Biology,Agriculture,"Biothechnology & Applied Migrobiology","Food Science & Tenology
Journal title
Bioscience, biotechnology, and biochemistry → ACNP
ISSN journal
09168451
Volume
57
Issue
8
Year of publication
1993
Pages
1400 - 1402
Database
ISI
SICI code
0916-8451(1993)57:8<1400:IOANRA>2.0.ZU;2-P
Abstract
We found a nuclear RA-binding activity by using a sucrose-density-grad ient assay from rat liver and testis. From the sedimentation analysis, and the comparison with cloned RARs, it is likely that these binding activities represent endogenous RARs. Furthermore we showed that these binding activities were constant irrespective of the retinoid status in the rat.