The distribution of alpha-tocopherol (alpha-Toc) stereoisomers in the
tissues of rats fed on a diet containing all-rac-alpha-tocopheryl acet
ate was investigated by a newly revised HPLC. The concentrations of 2R
-isomers of alpha-Toc in blood and tissues of the rats were significan
tly higher than those of 2S-isomers. In most tissues, the levels of 2S
-isomers were in order SRS>(SSS+SSR)/2>SRR.