SYNTHESIS OF C-14-LABELED SODIUM PARIPRAZOLE (E3810)

Citation
K. Tagami et al., SYNTHESIS OF C-14-LABELED SODIUM PARIPRAZOLE (E3810), Journal of labelled compounds & radiopharmaceuticals, 33(9), 1993, pp. 849-852
Citations number
4
Categorie Soggetti
Chemistry Analytical","Pharmacology & Pharmacy
ISSN journal
03624803
Volume
33
Issue
9
Year of publication
1993
Pages
849 - 852
Database
ISI
SICI code
0362-4803(1993)33:9<849:SOCSP(>2.0.ZU;2-3
Abstract
Sodium pariprazole (E3810), an inhibitor of H+,K+-ATPase, was synthesi zed labelled carbon-14, starting from 2-mercapto[2-C-14]-benzimidazole 1 a specific activity of 888 MBq/mmol. It was obtained in 49.3% radio chemical yield a radiochemical purity of more than 98%.