SERENDIPITOUS SYNTHESIS OF A CYCLOPROPANE-CONTAINING TAXOL ANALOG VIAANCHIMERIC PARTICIPATION OF AN UNACTIVATED ANGULAR METHYL-GROUP

Authors
CHEN SH HUANG S WEI JM FARINA V
Citation
Sh. Chen et al., SERENDIPITOUS SYNTHESIS OF A CYCLOPROPANE-CONTAINING TAXOL ANALOG VIAANCHIMERIC PARTICIPATION OF AN UNACTIVATED ANGULAR METHYL-GROUP, Journal of organic chemistry, 58(17), 1993, pp. 4520-4521
Citations number
28
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of organic chemistry → ACNP
ISSN journal
00223263
Volume
58
Issue
17
Year of publication
1993
Pages
4520 - 4521
Database
ISI
SICI code
0022-3263(1993)58:17<4520:SSOACT>2.0.ZU;2-E
Abstract
Treatment of a 7-epi taxol derivative with DAST in dichloromethane led to an unexpected reaction involving participation of the C-19 methyl group and clean formation of a cyclopropane ring.